What is the minimum score of globally aligning a protein with any other protein using some substitution matrix X?

02 February 2016 1 4K Report

Is there a calculation to obtain what is the possible lowest global alignment score for any protein? If I aligned protein y with all the proteins in the world, is there a limit of minimum score I can find?

Jeffrey R Brender

A lower bound is easy- it has to be equal to or greater than the score from a gap in every position.

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