Jeffrey R Brender

8 Questions 378 Answers 0 Followers

Questions related from Jeffrey R Brender

Are there any publicly available alternatives to the DUD docking set for benchmarking docking results?

Ideally something with a larger number of total compounds? I am aware of the MDL Drug Data Report database but this doesn't seem to be publicly available

05 May 2014 7,634 3 View

Request for assistance and possible collaboration: Database of the effect of small molecule inhibitors on amyloid aggregation

I am in the process of creating a database of experimental results of small molecule inhibitors of amyloidogenic proteins If you are interested in helping, there are two ways to get involved: 1....

02 February 2014 5,495 2 View

What concepts from dramatically different fields do you use in your research? What concepts in your field are useful for the non-major student?

In the first question, I am not talking about interdisciplinary research but specific concepts from very different field that you find useful in constructing your research even if it is not...

01 January 2014 5,644 7 View

Detection of protein or detergent micelles by a high throughput method?

I am looking for a relatively high throughput method of detecting the CMC of detergent or protein micelles. Does any one know of another high throughput method besides fluorescence or other...

09 September 2013 8,006 13 View

What new features would you like to see incorporated into the I-TASSER suite of programs?

Curious to see what people would like to see included in the next versions of the I-TASSER and related programs from Zhang lab (including I-TASSER (template based structure prediction), QUARK...

08 August 2013 9,012 10 View

Experimental variables that can be calculated from model protein structures?

I am looking at ways to validate experimentally to some degree the 3D structures of some theoretical models of proteins. What properties can be calculated from the structure that can be directly...

08 August 2013 5,558 4 View

Docking with orientational constraints?

Looking for a docking program that will allow orientational constraints between a small organic ligand and a larger protein. Experimentally, I know the relative orientation between the two by the...

04 April 2013 6,074 20 View

Amyloid protocols project

I have started a project to share protocols and methodological details on amyloids. For now, it would be located on this site and be open to anyone who wants to join (don't put proprietary...

02 February 2013 2,185 71 View