There seems to be a tacit assumption that electrons leaking from FMNH2 are transferred directly to oxygen. Is it possible that they first move into the matrix, become hydrated, and then react with oxygen? Any references on this?
Hello Jan,
this publication could give you some valuable information:
"Molecular mechanisms of superoxide production by the mitochondrial respiratory chain" by Dröse S, Brandt U, published in Adv Exp Med Biol. (2012)
doi: 10.1007/978-1-4614-3573-0_6.
Best regards!
Thanks, I have a couple of publications by these authors, not v. helpful so far, so I'll check the one you suggest
Regards, Jan
hi,
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