What is the maximum concentration of Zinc Oxide nanoparticles for application in bio-polymer based food grade packaging? I want to know the safe limit of Zinc Oxide nanoparticles for human consumption.
The lethal dose of zinc oxide for humans is approximately 27 g/day. It is stated that GI pain would occur far before reaching this limit.
In one case study, they found that a zinc oxide dose of approximately 7 mg/kg caused GI distress and diarrhea in adult humans.
Source is here: http://www.atsdr.cdc.gov/toxprofiles/tp60-c3.pdf
I hope that helps you develop a safe limit.
Thank you.
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