I am wondering if we have reported occurrence rate of hypercalcinosis and oxalate nephropathy in patients after any bariatric surgery? The rates of kidney stones after bariatric surgery now have been well reported. But I would like to ask if anyone can provide me the estimated rates of oxalate nephropathy and hypercalcinosis after bariatric surgery.
Thank you in advance,
Wisit
With RYGB or duodenal switch surgery, the patient has an increased absorption of oxalates from colon leading to enteric hyperoxaluria. The increase in oxalate absorption and subsequent excretion in this setting is related to fat malabsorption leading to unavailability of free calcium for binding oxalate in gut, and unabsorbed bile salt-induced increased colonic permeability to small molecules, such as oxalate.The complication of oxalate nephropathy is coming to light with increasing numbers of such operations. The diagnosis of oxalate nephropathy should be suspected in any patient who presents with sub-acute or chronic renal failure following bariatric surgery. Unfortunately, only a few case reports of oxalate nephropathy have been reported after bariatric surgery. In your clinic series of 60 cases of post-RYGB, only two had oxalate nephropathy and both reached end-stage renal disease (ESRD).
See :
J Am Coll Surg. 2010 Jul;211(1):8-15. doi: 10.1016/j.jamcollsurg.2010.03.007.
Hyperoxaluria is a long-term consequence of Roux-en-Y Gastric bypass: a 2-year prospective longitudinal study.
Duffey BG1, Alanee S, Pedro RN, Hinck B, Kriedberg C, Ikramuddin S, Kellogg T, Stessman M, Moeding A, Monga M.
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