I have a limited background in chemistry and need to synthesize particles that have functional EDA groups populated on the outer shell.
You can try hydrothermal carbonization approach. Please refer to the following link as an example.
Article Ethylenediamine-Assisted Hydrothermal Synthesis of Nitrogen-...
Hi Ryan,
You might use the functionalization of glucose-derived carbon nanoparticles with ethylenediamine as reported here: "Ethylenediamine functionalized carbon nanoparticles: synthesis, characterization, and evaluation for cadmium removal from water"
Another option is synthesize metallofullerene nanoparticles based on ethylenediamine -modified Gd@C82 via a facile solid–liquid coupling reaction (Gd@C82-(ethylenediamine)8 Nanoparticle: A New High-Efficiency Water-Soluble ROS Scavenger).
Another option would be to adapt a previously reported reaction. For example, Deng et al. used the a natural polysaccharide isolated from mulberry leaves as a nonviral gene vector (Efficient Gene Delivery to Mesenchymal Stem Cells by an Ethylenediamine-Modified Polysaccharide from Mulberry Leaves). Based on this reaction, you could use chitosan to obtain the nanoparticles.
Here are the DOIs of said articles:
Ethylenediamine functionalized carbon nanoparticles: synthesis, characterization, and evaluation for cadmium removal from water, RSC Adv., 2017,7, 34226-34235, 10.1039/C7RA04709F.
Gd@C82-(ethylenediamine)8 Nanoparticle: A New High-Efficiency Water-Soluble ROS Scavenger, ACS Appl. Mater. Interfaces, 2016, 8 (39), pp 25770–25776, 10.1021/acsami.6b08659.
Efficient Gene Delivery to Mesenchymal Stem Cells by an Ethylenediamine-Modified Polysaccharide from Mulberry Leaves, small 2012, 8, No. 3, 441–451, 10.1002/smll.201101554.
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