DOPAL is cathecolaldehyde resulting from dopamine metabolism, involved in Parkinson's disease ethiopathogenesis. ALR is one of the enzyme responsible for its detoxification, but we could not find information about the DOPAL affinity for it.
- All variables are continious (measure: scale) - I have added 4 variables (dependent, independent, mediator and control variable) - I'm using IBM SPSS Statistics 23 - I have used the following...
02 January 2021 1,091 2 View
Please provide references to papers in which alpha-synuclein concentration is estimated or to papers in which a suitable method to quantify protein concentration in neurons is applied.
22 January 2014 2,845 6 View
I am trying to find the fraction metabolized of a drug by CYP and UGT enzymes. I am unable to get the values of fraction metabolized (Fm) directly from the literature. Can we calculate the Fm of a...
21 February 2021 5,379 2 View
I am doing a project on classification of EEG signals of Alzheimer's disease and control groups. Previously, I extracted the alpha power of the EEG signals and found out the strengths. I want a...
18 February 2021 8,502 2 View
Hi, I'm asking from the point of view of designing a research plan: How long (approximately) can it take to determine the transition state structure of an enzyme substrate using kinetic isotope...
14 February 2021 2,610 1 View
I need to couple Dopamine by NH2 end to silica nanoparticles coated by PEG-NH2, but first i need to convert the PEG-NH2 to COOH by using succinic anhydrous ... can you suggest a reaction condition ?
13 February 2021 2,768 4 View
Hello, I am trying to find kinetic information (such as rate of enzyme production etc.) on the expression of taq polymerase in E-Coli after inserting a recombinant plasmid. Any help would be...
12 February 2021 1,386 3 View
I need a stack of black and white .jpeg/.tiff/.jpg/.png images across time of either action potentials, neurons firing, or brain scans (comparing disease and normal brain, disease progression,...
09 February 2021 2,648 3 View
Hello! I want to determine the activity of my in house Reverse Transcriptase enzyme. For this, I have used Thermo's Enzcheck Reverse Transcriptase assay kit. I used commercial Thermo RT enzyme to...
08 February 2021 7,285 1 View
07 February 2021 2,006 1 View
04 February 2021 278 4 View
Hi everyone, I need to clone in pGEM-T vector the result of amplifying a metagenomic library by PCR with a high fidelity polymerase but I only want to clone the fragments of an specific size...
04 February 2021 6,051 8 View