Nicoletta Plotegher

4 Questions 8 Answers 0 Followers

Questions related from Nicoletta Plotegher

What is the DOPAL affinity for aldehyde reductase (ALR)?

DOPAL is cathecolaldehyde resulting from dopamine metabolism, involved in Parkinson's disease ethiopathogenesis. ALR is one of the enzyme responsible for its detoxification, but we could not find...

05 February 2019 6,951 0 View

Does anyone know if product inhibition was reported for the enzyme glucocerebrosidase (GCase)?

Glucocerebrosidase (GCase) is a lysosomal enzyme (EC 3.2.1.45) encoded by GBA gene and responsible for the hydrolysis of glucosylceramides, an intermediate in glycolipid metabolism. The resulting...

04 April 2016 6,311 2 View

Does anyone know an estimate of alpha-synuclein protein concentration in neurons in physiological conditions?

Please provide references to papers in which alpha-synuclein concentration is estimated or to papers in which a suitable method to quantify protein concentration in neurons is applied.

23 January 2014 2,922 6 View

Does anyone know why Thioflavin S is mainly used to stain amyloids in tissue and cell culture, while Thioflavin T is used for in vitro detection?

It would be great to have also a reference where I can read something more about this issue.

21 May 2013 8,481 8 View