What is the difference between norepinephrine bitartrate, noradrenaline acid tartrate/norepinephrine acid tartrate, and noradrenaline tartrate?

20 June 2014 1 9K Report

USP 37 state CAS for norepinephrine bitartrate is [69815-49-2], BP 2013 state CAS for noradrenaline acid tartrate [108341-18-0] and EP 7 state CAS for noradrenaline tartrate is [108341-18-0]. Martindale 2006 state that noradrenaline acid tartrate have synonim: norepinephrine bitartrate.

Bridget Bengtson

similar chemical reactions and state but different systems: adrenaline is for striated or somatic system muscles "fight or flight" and epinephrine is for smooth muscle or autonomic "fight or flight" system. They are alike in different systemic functioning.

Badges
Science topic

If we increase norepinephrine levels in the body, will the dopamine level increase too? If yes, what is the mechanism?

Is there any mechanism by which nor-epinephrine gets converted back to dopamine in the brain?

31 December 2018 286 2 View

How can I know what the Norepinephrine re-uptake receptor concentration is (in the brain)?

I am adjusting a pharmacokinetic model and this could help me refine it. Thank you researchgaters!

09 October 2018 4,557 0 View

Is there a peripheral physiological signal/marker for serotonergic drive?

Although we can measure serotonin in peripheral blood, it may not reflect its activity in the central nervous system. Pupil dilation may serve as a marker for noradrenaline changes, but I can't...

22 March 2018 9,365 3 View

Is Norepinephrine essential for HL-1 cells?

Hello, I will start working with HL-1 cells to see if they have my protein of interest, I do not work in cardiac research but it has been difficult for me to find a cell with my protein (already...

02 March 2018 3,351 1 View

Why would a drug have no preclinical data (published)?

The drug in question is edivoxetine (a highly selective noradrenaline reuptake inhibitor). It reached phase III development where it failed to show significance in comparison to placebo. There...

01 February 2018 849 2 View

What concentration of Desipramine do you use to inhibit noradrenaline reuptake trasnporters?

I've added 6-OHDA to my neuronal cultures to test whether they are dopaminergic, and they do die. However, I was told that I need to also inhibit noradrenaline reuptake trasnporters as 6-OHDA is...

31 December 2017 9,903 2 View

HPLC plasma catecholamine and serotonin detection?

Hello everyone, I would really appreciate your help with an issue I am having. After successfully detecting and identifying catecholamines and serotonin in lizard brains using HPLC with UV...

09 October 2017 6,144 10 View

What are effective and long-lasting treatments for ADD (attention deficit disorder) / ADHD, excluding stimulants like amphetamines or SNRIs?

What are effective and long-lasting treatments for ADD (attention deficit disorder) / ADHD (attention deficit/hyperactivity disorder), excluding stimulants (like amphetamines, SNRIs, NRIs, or NDRIs)?

07 August 2017 10,016 13 View

Does N9 microglia cell line have serotonin/norepinephrine transporters?

04 May 2017 8,110 0 View

Does anyone know of any labs or services that would be interested in screening compounds on the human or rat norepinephrine transporter?

We have a few compounds that we would like to test for activity on these transporters.

08 March 2016 3,084 1 View