What is the correlation between H. pylori lacking Cag / Vac cytotoxin and induction of Wnt/β-catenin pathway in gastric adenocarcinoma ?

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How can we differentiate between calcite, dolomite, siderite, magnesite and ankerite minerals in carbonatite rocks in thin section under op microscop?

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Unusual intensity drop in some sections of chromatograms in DDA?

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Can you suggest reliable sources defining "3D mesh" and "3D city models"?

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Are air moisture harvesting technologies effective in combating desertification?

Air moisture harvesting Air water collection devices

06 August 2024 5,473 2 View

Absorption coefficient of methane?

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Dirty and clean?

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Can anyone provide me with molecular docking softwares/ websites?

Molecular docking software/ websites?

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What is the best sampling strategy?

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Senescence-associated beta galactosidase staining is False Positive in control group?

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What will be the best way to test NFkb activation via western blot?

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Does anyone know how to improve calcium-imaging fluorescence with GRIN lenses?

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Is it possible to quantify activity of the non-canonical Wnt signaling pathway via transcriptional readout genes??

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Beta galactosidase assay in milk?

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Beta cyclodextrin complex characterization methods?

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How to convert mIU/mL of beta galactosidase enzyme to pg/ml? I have used ELISA to determine beta gal concentration in mIU/ mL in human serum samples?

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How Can I Understand the Different Results from MacConkey Agar and β-Galactosidase Assays in a LexA-Based Bacterial-Two Hybrid System?

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What is the prognosis of nodular gastritis after nodular regression due to H.pylori eradication?

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Cleaved Caspase-3 antibody staining for IHC not working on FFPE tissues?

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Go J Yoshida

Cag-A transfected gastric mucosal cells with CD44v expression. become the cell of origin of gastric adenocarcinoma. CD44v decreases oxidative stress via CD44v-xCT-GSH axis, which is why CD44v-positive Cag-A transfected gastric mucosal cells clonally remain and proliferate as compared with CD44v-negative Cag-A transfected gastric mucosal cells. Furthermore, CD44v works as a negative feedback regulator against canonical Wnt signal activity triggered by oxidative stress.

Ref.

doi:10.1016/j.chom.2012.10.014

doi: 10.1016/j.bbrc.2013.12.016.

Ali Ibrahim Ali Al-Ezzy

dear Yoshida ,thanks alot