Hi Tunc, be sure about the path of your executable and path of log file. Alternatively you can just place the vina executable into a local folder and try.

 Dear Vikash,

You have just saved my finishing project.

Thank you very very much! :D

best regardsjavascript:

Tunc

Thank you Vikash Kumar, your recommendation solved my problem too.

Hi Vikash, Tunc and Samaria:

I have had the same problem but I do not how you guys based on Tunc comments said that his comments corrected your issue since I run into the same problem and although my path is C:\Program Files (x86)\The Scripps Research Institute\Vina.exe I get error message "UserError: "c:\"Program files(x86)"\"the scripps research institute"\vina\vina.exe" is not an executable

Service 'local:c:\"Program files(x86)"\"the scripps research institute"\vina\vina.exe' is unavailable. See Reply Log for more details." so I do not know what the problem is. Can you give me specific recommendation to correct the path?

After giving an output location and creating a grid box, see below; you will find four options, and one of them is executable location. Set the executable location as C:\Program Files (x86)\The Scripps Research Institute\Vina\vina.exe OR browse and choose the vina.exe file location in C-drive. Click OK, and your docking will be started. (see attached PNG file for better understanding).