I feel the best time is "exact medical fasting status". Reasons why i say that is the fact the basal medical rate is almost considered standardized for various biochemical parameters like glucose & lipid components included in the definition of metabolic syndrome.

Regards

If you intend to analyze pre & post dialysis anthropometric readings then paired sampling pre & post dialysis are suggested. However, you objectives can better define sampling times.

Regards

The diagnosis of metabloic syndromes requires the presence of 3 of 5 factors; these were abdominal obesity, elevated triglycerides, reduced HDL-C, elevated blood pressure, and elevated fasting glucose (IFG or type 2 diabetes mellitus). Therefore fasting sample is important.

I think Randomly

Dear Dr. Meaad

I agree with you, all blood sample must withdrawn in fasting state of patients for determination of Triglycerides, HDL and blood glucose levels.

Thanks for your answer

According to the NCEP ATP III definition, metabolic syndrome is present if three or more of the following five criteria are met:

• Fasting glucosegreater than or equal to 100 mg/dL
• Central or abdominal obesity (measured by waist circumference):
  • Men - greater than 40 inches
  • Women - greater than 35 inches
• Triglycerides greater than or equal to 150 milligrams per deciliter of blood (mg/dL)
• HDL cholesterol:
  • Men - Less than 40 mg/dL
  • Women - Less than 50 mg/dL
• Blood pressure greater than or equal to 130/85 millimeters of mercury (mmHg)

Yes, Akram M. Altaher

It has to be fasting and that too around 0800 hrs morning with three prior days of normal routine.....

If someone is taking any medicines to affect the metabolic parameters, i guess they may be stopped BUT after consultation of their physicians.

Regards

In hemodialysis patients, I would combine the measurements with the KT/V determination.

It may suspected that a person has metabolic syndrome if the person has excess weight around the waist and a sedentary lifestyle, but both laboratory and non-laboratory tests are important in establishing the diagnosis.

Recommended Laboratory tests include: Glucose, HbA1c and Lipid profile. other laboratory tests that are not recommended for diagnosing metabolic syndrome but that may ordered to provide additional information; C-peptide, urine albumin, hs CRP and small dense LDL. It is preferable that the person is fasting.

Non-laboratory tests: Blood pressure, Weight and waist circumference and BMI.

Metabolic syndrome would be diagnosed if 3 out the 5 criteria i.e high blood pressure, diabetes, obesity, High TG and low HDL

Please see the following links:

1.Metabolic Syndrome - Lab Tests Online

https://labtestsonline.org/conditions/metabolic-syndrome

2.Symptoms and Diagnosis of Metabolic Syndrome | American Heart ...

www.heart.org/.../metabolic-syndrome/symptoms-and-diagnosis-of-metabolic-syndrome

3. Metabolic syndrome - Symptoms and causes - Mayo Clinic

https://www.mayoclinic.org/diseases-conditions/metabolic-syndrome/.../syc-20351916

4. The Metabolic Syndrome . PDF

Please read this latest article. It will explain nearly everything for you.

Hormones (2018) 17:299–313: https://doi.org/10.1007/s42000-018-0051-3

Please refer to the following articles:

Kahn, R., Buse, J., Ferrannini, E., & Stern, M. (2005). The metabolic syndrome: time for a critical appraisal. Diabetologia, 48(9), 1684-1699.

http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.924.8712&rep=rep1&type=pdf

Cheţa, D. M. (2006). The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes: response to Kahn et al. Diabetes care, 29(1), 176-177.

http://care.diabetesjournals.org/content/diacare/29/1/176.2.full.pdf

Dear Abdullah

You have shared very relevant information and i totally agree with this.

Regards

It will be difficult to measure and diagnose metabolic syndrome in patients with ESRD.The components of MetS are all altered by ESRD. Blood pressure and lipid abnormalities (TG and HDL) are all significantly altered in MetS. The measurement of waist circumference is also variable and not reliable.

A prospective follow up of individuals with MetS to find out how often they develop CKD and ESRD may be a good option.

Thanks Akram.

Yes ESRD and CKD represent the late stages of the disease which have already been altered by met syndrome. So whatever data with regards to type and timings will be confounded by the disease.

Not also sure why diagnosing metabolic syndrome parameters pre and post dialysis will serve any purpose because dialysis monitoring parameters are already defined like urea kinetic remodeling.

Anyway the data will definitively be confounded by underlying renal disease. in agreement with George

Regards