Is it membrane protein? Cell division/cycle cycle protein , transmembrane protein/ DNA inhibitor or something else?
it should be decided after several trials to choice the effective different types of antibiotics as inhibitory substances by using discs diffusion test or well technique methods
based up on the results you can decided which antibiotics for example is the best for control or treatment
Most antibiotics that work on Gram-negative bacteria affect one of a small number of targets, including penicillin-binding proteins (which are membrane proteins) (beta-lactams), topoisomerases (fluoroquinolones), the ribosome (aminoglycosides, macrolides, tetracyclines and others), membranes (polymyxins), and folate biosynthesis (trimethoprim/sulfamethoxazole).
First-line antibiotic treatment for complicated (i.e. extraintestinal) Salmonella infections consists of the fluoroquinolone ciprofloxacin and the macrolide azithromycin. For uncomplicated (i.e. limited to the intestine) infections, antibiotics are not indicated. Supportive care for diarrhea and dehydration are indicated in those cases.
Gentamicin remains the drug of choice, but tobramycin may be preferred for Pseudomonas aeruginosa. Amikacin has the widest antibacterial spectrum of the aminoglycosides but is best reserved for infection caused by gentamicin-resistant organisms.
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