The effect of methyl bromide on humans and other mammals appears to vary according to the intensity of exposure. At concentrations not immediately fatal, this chemical produces neurological symptoms. High concentrations may bring about death through pulmonary injury and associated circulatory failure. The onset of toxic symptoms is delayed, and the latent period may vary between 0.5 to 48 hours, according to the intensity of the exposure and the personal reaction of the patient (von Oettingen, 1955). Contact of the human skin with the liquid or strong concentrations of the gas may cause severe local blistering (Watrous, 1942).

Against insects, methyl bromide appears to exert its principal toxic effect on the nervous system. As in humans, the onset of poisoning symptoms may be delayed, and with many species of insects definite conclusions as to the success of the treatment should be delayed for at least 24 hours. The comparative toxicity of this fumigant to some stored-product insects is given in Chapter 14, Table 16, and has recently been discussed by Hole (1981).

Richardson and Roth (1965) had some success with this compound against snails in military cargoes (see Schedule T). Methyl bromide is also effective against mites (Acarina). For grain mites, see Barker (1967a,b), and for cheese mites Burkholder (1966). In the treatments in which living plants and flower bulbs are tolerant, the eggs of mites may be resistant and repetition of fumigation may be necessary (see Schedules F and N).

I try fungi entomopathogen. Has anyone another openion about that?

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