What is the best measure of fatigue (in chronic fatigue syndrome) for a longitudinal treatment study?

More Emilie F. W. Raanes's questions See All

How should fully standardized expected parameter change (StdYX E.P.C. in Mplus CFA output) be interpreted?

And more specifically, how could I interpret a SEPC of 1.07? It points to a potential cross-loading. The two factors in question are highly correlated.

22 May 2024 5,381 2 View

Pricing as attribute in conjoint absolutely needed?

Hi! I'd like to run a conjoint analysis to understand the utility of each of my attributes for a specific prototype product. I was wandering if I absolutely need to put pricing as an attribute or...

30 November 2023 8,025 1 View

Why GFP bacterial strain do not fluoresce on some agar media ?

Have you already observed that some GFP strains do not fluoresce when they grow on certain agar media ? Do you know why, and what component of the media can interfere with fluorescence expression...

25 October 2023 2,449 1 View

What are the key feature between the species within the Sorex genus skulls and jaws use for skull and jaw identification?

Hello, I am currently working on identifying small North American mammal bones, I can ID down to the genus Sorex using the post-mandibular canal. Are there any key features that can help me...

02 July 2023 1,587 1 View

What can I do with an outlier without excluding the participant on SPSS ?

Hi, I am analyzing data from a survey with various measures. I have already done a selection on the sample to only keep participants who have completed all data (exclusion of any missing data). By...

11 January 2023 3,130 4 View

Does anyone know what are the circular-shaped transparent elements in culture ?

Hello, I'm currently cultivating patients' metastases in a medium supplemented in Penicillin and streptomycin and last week I observed the appearance of those circular transparent components. I...

01 January 2023 964 0 View

I have done an electrophoresis of white colonies from blue white screening. Why are there non-recombinant plasmids bands?

I have done a blue-white screening with E.coli and pUC19 with lambda DNA. Then, I selected some white colonies (and blue colonies as a control) and gel electrophoresed them next to pure pUC19. All...

13 November 2022 399 3 View

In Microbiology, how do you avoid R2B/R2A media with seawater to precipitate ?

I'm trying to prepare R2B/R2A media with seawater to cultivate marine bacteria after autoclaving (110°C) my media. I systematically observe a important precipitate. Despite many tests (in...

30 June 2021 2,715 3 View

Basal granzyme B level in inactivated CD8 T cells - flow cytometry?

Hello everyone, I'm currently analyzing expression of Granzyme B by T cells (CD4, CD8 and gamma delta) and NK cells and I found out that CD8, gamma delta T cells and NK cells express granzyme B...

14 January 2021 3,176 1 View

What is the dilution of the plasma to make an Elisa ghrelin with Phoenix pharmaceuticals kit ?

I have to measure the blood concentration of ghrelin with an Elisa. But in the Phoenix Pharmaceuticals kit I ordered, he asks me to dilute the sample without saying how many times. So has anyone...

29 September 2020 3,194 1 View

In the situation below, can I apply braun and Clark thematic analysis?

I have a theoretical framework for preparing a interview guide to assess the unmet care needs of a sub population of chronically ill patients and their caregivers(dyadic interviews).

04 August 2024 8,798 7 View

How are aPTT and PT values reduced after hemodialysis compared to before dialysis value in patients with chronic kidney disease?

I am conducting my research regarding blood coagulation in patients with CKD. I observed a reduction in post hemodialysis aPTT and PT values compared to pre hemodialysis values. But most of...

30 July 2024 3,467 0 View

How are doctors coping with the challenges of sleep deprivation and the demands of performing multiple emergency surgeries?

How do the physical demands of performing multiple surgeries in a single shift affect a doctor's overall health and longevity? How does the quality of patient care change when doctors are working...

02 July 2024 9,470 0 View

Can we use MTCMOS instead of CMOS for designing SRAM Latch ?

Basically CMOS are used for designing the SRAM cells . How the functionality will differ if we use Multi threshold CMOS instead of CMOS generally MTcmos decrease the leakage power but it will...

28 June 2024 9,845 0 View

I would like new suggestions on ways that can help me and on important skills to improve student performance?

I find a problem in teaching biology, especially since students begin to memorize information without concentrating just in order to get a good grade on the exam. Trying to use new and exciting...

26 June 2024 2,324 6 View

Nutrition map: What does it mean for you?

Unluckily, just similar to an expensive car, your brain can be damaged if you ingest anything other than premium fuel.

23 June 2024 2,287 7 View

Guidence for writing synopsis on aviation physiology pertaining to fatigue and stress of aircrew and how to optimize their performance?

i have wrote the tile of synopsis with reference to the current literature and top cited . kindly check below the titile. 1. optimizing overall performance of the aircrew through comprehensive...

15 June 2024 3,996 0 View

Batching process about FE-safe software?

I want to realize a auto-analyze process for weld fatigue by fe-safe software. However, I found that the current.macro in Tools can not record the commands of the GUI operation about defining the...

04 June 2024 5,089 1 View

Calculate sample size in cross-sectional studies?

I want to compare the RDW index between 2 groups of patients with stable COPD and COPD in acute exacerbations, so I calculated the sample size using the formula to estimate a ratio or compare 2...

02 June 2024 2,994 1 View

How planer biaxiality would affect the dynamic strain aging in SS 316LN during low cycle fatigue?

As the biaxial loading may implement additional hardening of the material during fatigue with an increase in the biaxiality ratio. What would be the effect of planer biaxiality on dynamic strain...

31 May 2024 9,104 0 View

Sławomir Kujawski

Dear Emilie,

If You are interested in PEM measurement than I think that “objective” measurement could be done using repeated CPET protocol or handgrip test. Respiratory exchange ratio during physical exercise is the only “objective” indicator of fatigue that I am aware.

Considering scales I would omit using Chalder Fatigue Questionnaire because of some of methodological problems in a longitudinal setting with this questionnaire [Wilshire, C.E.; McPhee, G.; Science for MECFQ. Submission to the public review on common data elements for ME/CFS: Problems with the Chalder Fatigue Questionnaire. Science for ME.].

Yours sincerely,

Emilie F. W. Raanes

Dear Sławomir Kujawski

Thank you very much, I appreciate your help.

Best regards,

Emilie