Iopidine (apraclonidine) was once used before as a prophylactic drug to prevent IOP spikes before and after glaucoma laser procedures but it seems now to be not in the market anymore
why not Dorzolamide or Brimonidine? Are there any studies to support this?
Brimonidine 0.2% (Alphagan), is similar to apraclonidine (alpha2 presinaptic agonist) in decrease the IOP peak post laser in anterior segment
ALPHAGAN-P ® (brimonidine 0.15% + purite ophthalmic solution) also works well for prevention of IOP spikes post ant. segment laser surgeries.
Reference:
Yeom et al. Brimonidine 0.2% versus brimonidine Purite 0.15%: prophylactic effect on iop elevation after Nd:YAG laser posterior capsulotomy. J Ocul Pharmacol Ther. 2006 Jun;22(3):176-81.
I don't think there is one sure shot answer to your question. It depends on the experience of the clinician. Also certain patients show good effects with one medication and some show with others. I think it will be better for you to just ponder upon your own experience. That should be the guiding principle rather that slight differences in pharmakodynamics etc.
- Badges
- Science topic
- Similar topics
- Chemistry
- Pharmacology
- Medical Pharmacology
- Clinical Pharmacology