Physical reality can be observed. At least part of the structure and behavior of physical reality is perceivable. Humans can communicate about these experiences. Curious humans want to comprehend these perceptions. Humans have designed linguistic tools to be able to communicate about the perceived structure and behavior of physical reality and with these tools, they have constructed structures and models of mechanisms that might explain the perceived structures and mechanisms that physical reality exposes. Some of these structures and models of mechanisms seem to be successful. People discuss the success of these approaches and call this activity exact science. Other humans discuss this activity and call themselves philosophers. Humans are interested in the structure and mechanisms of physical reality because this knowledge helps them survive as individuals and as communities. Part of the exact sciences is formed by mathematics. Mathematics contains structures and models of mechanisms that are not directly derived from perceptions of physical reality. These concepts are derived from abstract foundations. Examples are empty space and point-like objects. Scientists use these concepts to construct vector spaces, number systems, and coordinate systems. The scientists apply these higher-level concepts to construct a model of their living space. The philosophers will immediately indicate that it is impossible to prove that these models are correct. However, these models feature structure and behavior. If the structure and behavior of the models agree more with the perceived models and behavior, then there is a larger chance that the model fits reality. Since reality appears to be very complicated, little chance exists that good correspondence will ever end the dispute.
One of the aspects of the dispute concerns what the best inroad will be for comprehending most of the structure and the mechanisms of physical reality. That is the background of the posed question.