How to functionalise the surface of a PMMA microparticle with amines?

Theatin van Leeuwen @Theatin-Van-Leeuwen

14 June 2024 1 8K Report

I have porous PMMA microparticles up to 1mm in diameter.

I would like to functionalise the surface with amines whilst keeping the particles intact.

Chat GTP has recommended ethanolamine or ATPES but I cannot find any articles that directly reference this. I am open to other methods too.

CuO nanoparticles are also present in the PMMA so I do not want to degrade those either.

Let me know if any thoughts or know of any papers for reference.

Thank you!

Abdelkader BOUAZIZ

Dear Theatin van Leeuwen, do search with "aminolysis of PMMA particles. This kind of protocols are widely used in the field of drug delivery. My Regards

https://doi.org/10.1002/jbm.a.10047

https://doi.org/10.1016/S0168-3659(03)00005-1

Amination references in:

https://www.researchgate.net/publication/321739510_Simplified_Immobilisation_Method_for_Histidine-tagged_Enzymes_in_Polymethyl_methacrylate_Microfluidic_Devices/figures?lo=1&utm_source=google&utm_medium=organic

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