Hi Somayeh,

Magnetofection is working pretty well and particularly Neuromag for primary neurons transfection.

Please let me know if you need more information.All the best.

Dear Somayeh,

I am totally agree with Romuald since we have developped this powerful reagent NeuroMag (based on the Magnetofection*** technology) as an alternative to "classic" transfection methods that can be harmful for neurons.

Initially deelopped for primary hippocampal and corticla neurons, NeuroMag was demonstrated to by highly efficient:

• on primary Neurons from diverse terrtiories (hippocampal, cortical, motor neurons, dorsal root ganglion, cerebellar granules…) and diverse origins (rat, mouse, human…)
• For any DIV: from DIV 1 to DIV 21
• On “neuron cell types” from neuronal cell lines (such as C6) to astrocytes, and even Neural Stem cells
• With any nucleic acid, from large plasmid DNA to short siRNA or ODN,
• And moreover, as this reagent is non-toxic at the recommended doses, transfection effect can be followed up to more than 7 days.

For published scientific articles that use NeuroMag to transfect any neurons you can have a look at our citation database in the following link.

I am pretty sure NeuroMag will be of high interest for your transfection experiment, and please do not hesitate to contact me via ResearchGate of directly at: [email protected] for any information,

good luck with your experiment,

Cedric

MAGNETOFECTION

*** The Magnetofection technology uses a magnetic field to attract and concentrate complexes of magnetic nanoparticles and nucleic acid onto the cell surface as demonstrated by Grześkowiak BF et al, Pharm Res. 2014 Jul 18. (http://www.ncbi.nlm.nih.gov/pubmed/25033763).

http://www.ozbiosciences.com/module/citationfinder/default