Research on progress of this condition, course of growth, treatments.
Cystitis cystica is frequently seen in Egypt as well as in other African countries (Sudan, Kenya and Tanzania) and some Asian countries where fresh water snails are functioning as an intermediate host for the trematode Schistosoma Haematobium. Once in the human body, the cercariae of Shistosoma Haematobium find their way to the urogenital tract. One of the pathognomonic signs is the presence of cystitis cystica in the bladder of an infected person. it responds to the treatment of Schistosomiasis which is Prazequantel 60 mg/Kg body weight (for an adult) However, the lesions might not disappear when well developed, since it is a form of central degenration in a granuloma
Cystitis cystica is a response to chronic irritation of the bladder and marked by the presence of slit like spaces in the lamina propria of the bladder wall. It is to be distinguished from cystitis glanularis. The intestinal type of the latter is important as patients with extensive type of intestinal metaplasia are at risk of adenocarcinoma.
Thank you Deepak. I think that malignancy or potential for malignancy the number one concern of people. What about the situation where someone converts from the glanularis type to cycstica type? And, Is there such a thing as combined types?
Janet D'Arcangelo
Thank you Janet. It is not uncommon to find the two coexisting in a bladder. In fact the two are often discussed as a combined entity- Cystitis cystica et glandularis. This is not unexpected due to the common root of origin, namely irritation of the mucosa. As glandularis changes, especially intestinal metaplasia (IM) may be patchy, one may find no evidence of IM at a subsequent biopsy. It is difficult to be sure, and the random nature of biopsies may contribute to these so called changes in the histological picture. If overall, no IM is found at many subsequent biopsies, it heralds good news.
Cystitis cystica is simply a benign finding in a number of bladder conditions. Of itself it does not require treatment. You manage the symptoms (OAB) or (if recurrent proven UTIs) treat with antibiotic prophylaxis. Otherwise ignore it !
Thank you all for the informative answers as to description, treatment and prognosis
I learned a lot and have more directions to research the literature.
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