What could be the mechanism of degradation of polycarbonate/graphene nanocomposites ?

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What should i use to align molecule for QSAR?

I have molecules with different groups. Some are bis chalcones, some are Dicoumarins, etc. How do I align them in Sybyl software if I can't select any common template?

27 June 2024 7,085 1 View

What method or machine learning algorithm can be used?

I have the molecule's activity value and molecular descriptors. How can I find out which descriptors are the main components for increasing the activity of molecules? also, what Machine learning...

29 May 2024 4,169 2 View

Enhanced expression of housekeeping gene GAPDH in transfected HEK293 cells?

Hello Everyone. I see an enhanced expression/secretion of the housekeeping gene GAPDH gene in my transfected HEK293 free-style cells. I am 100% sure that I normalized the amount of loaded samples...

20 March 2024 3,216 1 View

What could be the problem of tz-mbl assay?

I am doing Tz-mbl assay(beta-galactosidase assay) for evaluating anti-viral activity for hiv infection. When I am doing with p24 assay is coming good but when I am doing it in tz-mbl assay I am...

22 September 2023 5,377 0 View

What assay can I perform?

I want to check inhibition activity of small molecules against HIV-1 entry. What assay I can perform other than fusion assay?

17 September 2023 5,190 4 View

What are other procedure for antiviral assay for HIV?

I want to perform an antiviral assay for HIV inhibitors. I can't do the p-24 assay and I can only do the beta-galactosidase assay. So which cell lines can I use for this other than the tz-mbl cell?

16 July 2023 6,856 2 View

How I can get permission to use Groningen Frailty Indicator or Tilburg frailty indicator, Age-adjusted Charlson Comorbidity Index for reseach work?

kindly reply to my Email ID- [email protected].

25 May 2023 2,241 0 View

Data analysis problem?

I have two different data table of molecular descriptors of small molecules according to their activities. I want to compare those two datasets and see if there is anything common features between...

01 May 2023 8,658 1 View

How to compare two different datasets to find out the common features among them?

I have two different data table of molecular descriptors of small molecules according to their activities. I want to compare those two datasets and see if there is anything common features between...

15 April 2023 5,350 1 View

How to make changes in BURAI's input file before run?

I have picked a structure of 50-100 similar atoms and put this structure in BURAI software to find its Density of States (DOS). What changes should I make in its input file before run. what is the...

02 April 2023 8,684 0 View

The Optimal Experimental Approach for Gene Function Analysis?

What is the most suitable experimental setting to understand the consequences of a particular gene: (1) targeted degradation of the specific transcription factor (TF) of the gene, followed by...

04 August 2024 6,265 1 View

Short Synthesis of Graphene Oxide from Natural Graphite Flakes?

I am in search of a modified Hummer's method, which can be used to synthesis graphene oxide within 6-8 hours. As I am a student it is not allowed for us to work after 5 in the laboratory. So I am...

01 August 2024 8,368 2 View

How can I separate graphene from amorphous carbon of similar particle sizes?

The starting material is a finely ground powder. Some particles contain more graphene than others.

30 July 2024 3,978 2 View

Culture fibroblasts with or without FGF2?

I'm new to primary human fibroblast culture and I'm studying aging using cells from old and young donors. Some research groups have used media supplemented with FGF2, so I cultured cells in the...

29 July 2024 3,030 2 View

What is the best method to detect the chemical composition of pollen ?

I have multiple small samples of grass pollen with anthers. I want to find a method to identify concentrations of proteins, lipids, and other various elements for these samples. any suggestions?

28 July 2024 5,331 1 View

Please introduce me the latest published articles on the structure and properties of metal nanocomposites?

26 July 2024 2,200 3 View

How to separate the stereoisomers compond in reaction mixture?

how to separate the organic reaction stereo isomers compounds are separate from the reaction mixture any simple methods are available

23 July 2024 8,025 4 View

How should we increase the quality of RNA extraction?

I’m having difficulty achieving high RNA integrity in my samples. Although the 260/280 and 260/230 ratios are satisfactory after RNA extraction, the RNA samples show signs of degradation when...

22 July 2024 155 4 View

Hi dear researchers, do you suggest the best and shortest path for chemical synthesis and green synthesis of magnetite(Fe3O4)?

Suggest the best and shortest route for the chemical synthesis and and green synthesis of magnetite(Fe3O4) The chemical synthesis should contain the least dangerous chemicals along with full...

21 July 2024 2,476 2 View

Why do fish have fishy odors naturally ?

Chemical Engineering /Food Engineering

20 July 2024 4,152 4 View