What change occur for signaling pathway of liver tissue during aerobic exercise ?

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Peter Griepink

cAMP will activate PKA, and this on its turn LKB1, which activates AMPK. AMPK would block mTOR singnaling. So I assume they are linked.

Entedhar Sarhat

Maybe the following papers will help you:

1. Murray, Michael, "The Effect of Aerobic Exercise Training on Hepatic Glycogen Metabolism in Type 1 Diabetic Rats" (2015). Electronic Thesis and Dissertation Repository. 2726.

2. Woo JH, Shin KO, Lee YH, Jang KS, Bae JY, Roh HT. Effects of treadmill exercise on skeletal muscle mTOR signaling pathway in high-fat diet-induced obese mice. Journal of Physical Therapy Science. 2016;28(4):1260-1265. doi:10.1589/jpts.28.1260.

3. Elijah Trefts, Ashley S. Williams, and David H. Wasserman.Exercise and the Regulation of Hepatic Metabolism.Prog Mol Biol Transl Sci. 2015; 135: 203–225.

4. Trefts E, Williams AS, Wasserman DH. Exercise and the Regulation of Hepatic Metabolism. Progress in molecular biology and translational science. 2015;135:203-225. doi:10.1016/bs.pmbts.2015.07.010.

Li Yin, Cuifang Chang, and Cunshuan Xu, “Expressions Profiles of the Proteins Associated with Carbohydrate Metabolism in Rat Liver Regeneration,” BioMed Research International, vol. 2017, Article ID 8428926, 9 pages, 2017. doi:10.1155/2017/8428