co-ordinates are nothing but they are 3D location, as we have 3 axis X, Y and Z. So consider X as anterior, Y as lateral and Z as ventral from Bregma. 

For locate any disease specific co-ordinate let me know disease or condition which you want to induce in animal.

It's depends upon what exactly you want to do, like for PD and AD all coordinates are different.  Even you can find out this in rate atlas very easily. 

I am inducing Alzheimer's disease and I have no access to brain atlas.

Ok I have articles for AD, which mentioned all coordinates very properly.  I will send you that articles soon which could help you. 

Thanks a lot for your kind help

I think now you got your answer.

Try on this link: https://gaidi.ca/rat-brain-atlas/

Good luck.

I also need the coordinates for lateral ventricle to induce mania-like behavior by injecting ouabain. I've been having problems with the injection and i think the problem is on the coordinates! The atlas for SD gives the coordinates for animals up to 250g of wight, but i've been using animals 350-400g. Would the head/brain grow enough for changing the coordinates of lateral ventricle?

Thanks!

Dear Mahmoud,

would you mind to find some (more) specific questions and answers in a series of similar requests in RG, e.g. by pasting into your browser (when on RG):

https://www.researchgate.net/search.Search.html?type=question&query=rat+brain+atlas   ?  You'll find a lot of similar questions and hopefully also answers.....

Dear Maria: practise, the coordinates are the same for animals up to 250 g.

Good luck.

Beatriz

. 

Dear Beatriz

If we can use the same co ordinates for animals upto 400  g, why the atlus is strict to use coordinates  upto 250 g?

Thanks

Smriti

I was thinking the coordinates would be the same, but since the injections are failing, I don't know what else could be :/

Dear Carolina Bittencourt, the brain/cranium growth is enough to change the coordinates of LV (and other areas). Since the atlas was designed from rats weighing 270 +_ 20 g, although can be utilized for rats between 250 and 350 g with minimal variation (less than 0.1 mm). Thus, you must utilize rats in this weigh range or validate the LV coordinates when using mature animals.

Try looking for it in the rat brain atlas developed by Watson and Paxinos

Dear all,

Thanks for all the answers.

Watson & Paxinos is a major atlas for Wistar rats.

However, in the past years (after joining this discussion) I've succeeded by using the Waxholm Space Sprague Dawley rat atlas of Papp et al. (2014) , which has an online version available at https://scalablebrainatlas.incf.org/. I tested different coordinates based on this online tool and it was pretty much accurate!

Whomever needs to perform stereotaxis in Sprague-Dawley rats, I encourage trying it.

Best,

Maria