Maria Carolina Bittencourt Gonçalves

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Questions related from Maria Carolina Bittencourt Gonçalves

What is the best/easiest way to measure lithium levels in blood samples from an animal model for bipolar disorder?

I'm working with animal models for bipolar disorder to investigate lithium mechanisms of action. However i've been using lithium dosage based only in the suggestions from the literature. Indeed, I...

25 April 2016 2,672 3 View

What's the difference on using either Sprague-Dawley or Wistar rats for modeling manic behavior?

I want to mimic the manic/euphoric behavior in rats by ouabain induction protocol but I've found both Sprague-Dawley and Wistar rats being used for that. Which could be the best choice and why? Tks

10 February 2015 2,589 1 View

Is it okay to homogenize brain tissue with ultrasonic waves before following TRIzol's protocols for RNA, DNA and protein extraction?

I need to isolate RNA, DNA and protein from lots of samples of hippocampus and pre-frontal cortex obtained from adult rats. Would there be a problem if I were to use ultrasonic waves to homogenize...

04 October 2014 9,257 7 View

Which tissues express all the purinergic receptors?

Hi guys! I'm having some difficulties to find a tissue(s) that expresses all the purinergic receptors of P1(a1, a2a, a2b and a3), P2X(1-7) and P2Y(1,2,4,6,12 and 13) families, to use as a positive...

01 October 2014 8,535 4 View