According to the study titled as: Umbilical cord blood: Current uses for transfusion and regenerative medicine published by Nicoletta Orlando and her team is that the umbilical cord blood can be use as an alternative for bone marrow for as a source of hematopoietic stem cells for curing and therapy of chronic diseases.
is there any specific qualifications for the umbilical cord blood to become an allogeneic donor for hematological patients?
Article Umbilical cord blood: Current uses for transfusion and regen...
Good Day!
To answer your question, a study was conducted by Dehn, J. et. al. entitled "Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: guidelines from the NMDP/CIBMTR" which introduces "selection guidelines" for Unrelated Cord Blood (CB) Units. The authors described that the "Optimal CB graft selection criteria must consider unit quality and cryopreserved cell dose, as well as HLA match." They also added that the "unit quality is a result from banking practice that has increasingly been recognized as a critical factor in unit selection because unit quality is highly associated with unit potency, including postthaw CD34+ cell viability and recovery."
I hope this answer your question. Also, here is the reference of the following study. Dehn, J. et. al. (14 December 2020). Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: guidelines from the NMDP/CIBMTR. ScienceDirect. Retrieved February 23, 2022 from https://www.sciencedirect.com/science/article/pii/S0006497120714114
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