If you could name the most important publications relating to any of the biological sciences over the last 100 years what would those be? Beginning with Francis & Crick's paper on DNA...
you may like this wonderfull interactive website "DNA from the beginning" (http://www.dnaftb.org/). There are most important experiments in Genetics and Molecular Biology beginning from J. G. Mendel discovery of inheritance laws. All 75 experiments are supported by original publications in "LINKS" section.
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid J. D. WATSON & F. H. C. CRICK Nature volume 171, pages 737–738 (25 April 1953) | that is most likely the most important paper in the era of biology after Darvin's books.