Check this database.

http://www.camag.com/en/tlc_hptlc/customer_magazine_cbs/ccbs_database.cfm?method=query

Thanks a lot..

Metformin Hcl freely soluble in water, Methanol and slightly soluble in ethanol

Ciprofloxacin can dissolve in Water, ethanlol, 2-propanol, acetone to get retention factor in TLC

Also find sites

pubs.acs.org/doi/abs/10.1021/ie8003495 pubs.acs.org/doi/abs/10.1021/ie8003495

www.sohanhealthcare.net/metformin-hydrochloride.htm

Md. Rajdoula Rafe,

A technical hint: use a solvent that is fast evaporating (like acetone or methanol) this will allow you to obain small spots on the plate.

regards,

G

Thank you ...

Metformin Hydrochloride is freely soluble. Not suddenly it will soluble requires some time.