The X-linked red-green color blindness is the most common type of vision impairment. It shows a recessive nature of inheritance and obviously it is genetic, not acquired. But careful design should be made by taking other confounding variables such as life style, food habits, environmental stress etc to predict the most effective one . The frequency of CVDs may be high in some tribes or castes, who don't allow their members to marry outside. So, population studies, especially in Pakistan, you must look for family pedigrees and the coefficient of inbreeding as well to ensure the statistical significance..!

If you are calculating gene frequency than take only non-inbred subjects of each population.

thanks fareed fo nice information.

we already have included our objective to see about impact of consanguinity upon color blindness.

X-linked most common- but there are so many variants and genetic transmission can include all spectra..

Dear Muhammad Shoaib Akhtar     

I will address the risk factors for "acquired" color vision deficiencies. 

Chronic illnesses which can lead to colour blindness include Alzheimer’s disease, diabetes mellitus, glaucoma, leukaemia, liver disease, chronic alcoholism, macular degeneration, multiple sclerosis, Parkinson’s disease, sickle cell anaemia and retinitis pigmentosa.

Accidents or strokes that damage the retina or affect particular areas of the brain/eye can lead to colour blindness.

Medications such as antibiotics, barbiturates, anti-tuberculosis drugs, high blood pressure medications and several medications to treat nervous disorders may cause colour blindness.

Industrial or environmental chemicals such as carbon monoxide, carbon disulphide and some containing lead can also cause colour blindness.

Age – in people over 60 years of age physical changes can occur which might affect a person’s capacity to see colors i.e. cataracts.

Ref:   http://www.colourblindawareness.org/colour-blindness/acquired-colour-vision-defects/

I have attached the PowerPoint Presentation I gave at the Aerospace Medical Association in 2012. It's intent was  to help differentiate between congenital and acquired color vision deficiencies.  The PPP introduces an innovative computerized color vision test (full disclosure: I have a financial interest in the computerized test). 

I hope you find this helpful.

Regards, Terrace Waggoner, O.D.

Hi,

You are not mentioned, you are constrating on Adult population or in Infants.  Ok  any way see the links.

Kindly see the following links:  Genetic Risk Factors of Color Vision Deficiency

http://bodyandhealth.canada.com/condition_info_details.asp?disease_id=36

http://www.healthcommunities.com/color-vision-deficiency/causes.shtml

http://pediatrics.med.nyu.edu/conditions-we-treat/conditions/color-blindness

thanks Terrace Waggoner and Sentilvel.

hope it will be helpful to me.