What are human macrophage surface markers for discrimination between M1 and M2 phenotypes?

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Ting Yu

M1 refers to CD11c+, while M2 refers to CD206+ or CD163+. Soluble CD163 (sCD163) could be considered as serum marker.

Samantha Le Sommer

At least surface marker wise a lot of people argue over this issue till the cows come home, though for my PCR to look at M1 v M2 I also include Ki67, RELMalpha, Ym1 and CSF1

Ruixian Liu

compared to surface markers, cytokine profiles may be more useful to distiguish M1 and M2.

M1: IL10low, IL12high ,CXCL9,10+

M2:IL10high,IL12low