If you want to see the fine structure  of the membrane (i.e. the symmetry of the glycoprotein of the capsid) use transmission electron microscopy. If you want to see the localization of a particular protein use immunogold TEM or fluorescence microscopy. 

If I were you I would stick with electron microscopy, because fluorescence or confocal microscopy is good when you want to investigate tissues with cells interacting each other. In a virus you need high magnification and resolution of EM to see what is going at protein expression level.

best wishes, Refik

For living tissues, the fluorescence technique is primarily indicated. It uses fluorophores that have large absorption cross-sections at a specific wavelength and emit light at a longer wavelength. Because of the combination of high absorption cross-section and high quantum efficiency, fluorophore labeled molecules are very bright and readily distinguishable from other background signals. This optical property makes it fairly straight forward to obtain images of the labeled molecules with high contrast.

Dear Glenda,

ONe of the best thing about fluorescence microcopy is the abilirt to label upto 4 even 5 different target simultaneously in the same sample.

best wishes,

Refik