I'm interested in starting some cell culture studies of human pericytes. A web search turned up several vendors with the sources of pericytes being brain blood vessels or placenta. Are there major advantages/disadvantages for either? Also can anyone recommend a specific vendor/product.
Dear Donald,
I have used the fetal human brain vascular pericytes from ScienCell (cat 1200) for several years with good results. Their website doesn't state that they are isolated from fetal tissue but the company told me when I asked for more specifications. There will probably be a slight difference in markers expressed by pericytes isolated from placenta and from brain so it depends on the purpose of your study. Hope this helps!
Thanks very much. Do these cells express PDGFR-beta? I want to use the cells to study mechanisms relevant to cardiac pathophysiology. Are they easy to grow and how many passages can you use?
Yes they express PDGFR-beta. They are very easy to grow and I think Sciencell guarantee that they are good to expand for 15 passages. Good luck!
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