Trends in bioinformatics application in drug discovery

Ajit kumar Roy @Ajit_Roy

01 January 1970 0 4K Report

trends in bioinformatics application in drug discovery for cancer,HIV-AIDS,Ebola

Badges
Science topic

More Ajit kumar Roy's questions See All

Do you agree that Emotional Intelligence impact on Professional excellence?

Valuable answers are requested.

31 December 2018 8,702 3 View

Do you believe AI and Automation Will make many jobless?

Input requested.

10 November 2018 8,506 2 View

Do u believe Neural network forecasts exceeded other traditional forecasting methods?

Traditional forecasting methods like linear or logistic regression systems is surpassed by Neural network forecasts in determining predictor variables?

09 October 2018 325 0 View

Can anyone differentiate between human intelligence and artificial intelligence?

Input requested from RG members.

09 October 2018 6,590 6 View

Can anyone mention the beneficial effect of fish Hilsa ilisa?

Many people believe that frequent eating of the fish controls heart disease.

08 September 2018 2,012 5 View

Can anyone explain the procedure of constructing variables from concept?

In social sciences often use concepts that are more abstract and therefore the standardization in measurement is needed following a standard methodology.

08 September 2018 5,927 4 View

Do you feel Emotional intelligence and academic achievements is related?

Wise thoughtful input requested.

08 September 2018 226 18 View

Can anyone suggest how to perform Kernel regression in SPSS?

Suggestions requested for RG members.

08 September 2018 6,985 1 View

How to Choose a Correct Statistical Test?

Can anyone highlight on this crucial AREA.

07 August 2018 1,109 3 View

What are the reasons that girls drop out of school?

What are the likely consequences of drop out of schools?

07 August 2018 7,707 40 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

What is the difference between genotype and haplotype data in the ped format?

Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...

27 February 2021 1,965 1 View

Why is the efficiency of viral mRNA electroporation in PBMC low?

Hello, I have been struggling with the electroporation of PBMC with HIV-I mRNA. Although the quality of the RNA generated is good, and the handling of the cells in meticulous, the frequency of...

27 February 2021 9,233 3 View

How to empty large intestine in mice ?

Hi all I am working on colon-targeted drug delivery for which I kept mice fasting for 6h using fasting grills during scotophase (dark period). I observed liquid fecal content in the cecum and...

23 February 2021 7,701 2 View

Can I use a protein-devoid condition as my negative control in ELISA?

Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...

23 February 2021 7,429 1 View

How does the injection volume impact LLOQ and ULOQ in regression analysis (LC-MSMS)?

Hello, I have run into an issue that has sparkled a debate at work: is the LLOQ/ULOQ impacted by injection volume under the following circumstances: 1) Same dilution factor of all samples 2)...

23 February 2021 9,159 3 View