The correlation between fish (freshwater) bioaccumulation to damage fish organs (gills, kidney, liver, mussels) it seen biopsy? if possible means why it occurred what is function happened in biological activity... can explained in detail to discussion of biological actions.
Different chemicals have different target organs. Effect depends not only on bioaccumulation, but also chemical dose, exposure, etc. Also, some elements can increase or decrease toxic action of other elements. For example, together U and Cd have less toxicity than they must have.
Yes it is true combined action of toxicants may reduce the toxic effect of induvidual chemical effect on organans/tissues.
Yes, but the strength of that correlation can be extremely variable. You should look at the literature dealing will "Critical Body Residues (CBR)" or "Lethal Body Burdens (LBB)" in fish. These relate internal body concentrations to observed effects. Note, however, that these internal concentrations generally must be expressed in specific units. For example, for organic chemicals the units of choice is umol/g wet weight or its equivalent. I hope this helps.
May these documents be useful for you (see attached files).
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