The drug vinpocetine is currently being promoted in Slovakia by certain pharmaceutical company for use in psychiatry. Vinpocetine has a rich history and is mainly used to improve cognitive function after vascular insults/pathology of brain. Does anyone have experience with it in the treatment of cognitive impairment within psychiatry, or in any other indication? Is there any strong clinical reason to resurrect this drug, so to speak? Does it make sense to give it for cognitive symptoms, e.g. in patients with affective disorders? Does it make sense to combine it with ginkgo biloba extract? What are your experiences?
Article Effect of Vinpocetine (Cognitol™) on Cognitive Performances ...
This is one of the inconclusive results that support the use of vinpocetine in neurology (patients with epilepsy), but in patients with dementia, the efficacy was minimal...
Hi,
Maybe some of these articles of help:
Perng CH, Chang YC, Tzang RF. The treatment of cognitive dysfunction in dementia: a multiple treatments meta-analysis. Psychopharmacology (Berl). 2018 May;235(5):1571-1580. doi: 10.1007/s00213-018-4867-y
Sharif S, Guirguis A, Fergus S, Schifano F. The Use and Impact of Cognitive Enhancers among University Students: A Systematic Review. Brain Sci. 2021 Mar 10;11(3):355. doi: 10.3390/brainsci11030355
Zhang YS, Li JD, Yan C. An update on vinpocetine: New discoveries and clinical implications. Eur J Pharmacol. 2018 Jan 15;819:30-34. doi: 10.1016/j.ejphar.2017.11.041
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