The mutations in the adducin gene ids known to relate with the onset of hypertension, how does this happen?

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Amanpreet Badhwar

Adducin is a cytoskeletal component. Mutations in alpha-ADD1 has been associated with essential hypertension and greater sensitivity to changes in sodium balance. An informative review on the topic is the 2015 meta-analysis provided below:

Association of alpha-ADD1 Gene and Hypertension Risk: A Meta-Analysis.

http://www.ncbi.nlm.nih.gov/pubmed/26042478

Javan Ochieng Okendo

Thanks, Amanpreet Badhwar, can you help me get the primers for the alpha-ADD1 genes? if you have an article then kindly send me the link