Scopolamine is used widely in drug discovery for neuronal disease but little is known about how it works exactly. What is the signal transduction pathway after blockade of muscarinic acetylcholine receptors by scopolamine and what happens before it finally induces learning and memory deficit?
Jaromir Myslivecek
There is no scopolamine pathway. The answer is involved in your question. Scopolamine blocs the signaling via muscarinic receptors and as there is general need for balance between brain neurotransmiter systems signaling, scopolamine would cause disbalance between sytems (e.g. muscarinic and dopamine) and therefore functional deficits.
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