Why Scopolamine is mostly used as for inducing amnesia in pre-treated animals? I was wondering why no study is available there, to use scopolamine in pre-treatment manner for a duration and then reverse the amnesia effects, using control and novel drugs in a post-treating manner to ameliorate the deficits of scopolamine?
I would be thankful for any hints or info.
Hi, Have you looked at this article: Naglie, G., Tansey, C., Kirkland, J. L., Ogilvie-Harris, D. J., Detsky, A. S., Etchells, E., ... & Goldlist, B. (2002). Interdisciplinary inpatient care for elderly people with hip fracture: a randomized controlled trial. Cmaj, 167(1), 25-32.
Levin, E. D., & Rose, J. E. (1991). Interactive effects of D1 and D2 agonists with scopolamine on radial-arm maze performance. Pharmacology Biochemistry and Behavior, 38(2), 243-246.
Levin, E. D. (1988). Scopolamine interactions with D1 and D2 antagonists on radial-arm maze performance in rats. Behavioral and neural biology, 50(2), 240-245.
Rezvani, A. H., Cauley, M., Sexton, H., Xiao, Y., Brown, M. L., Paige, M. A., ... & Levin, E. D. (2011). Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague–Dawley rats. Psychopharmacology, 215(4), 621-630.
- Badges
- Science topic
- Similar topics
- Geoscience
- Asia
- India