For now I consider the best way of docking in Schrodinger Maestro package. I have three types:
1. Grid preparation -> Glide -> Prime MM-GBSA.
2. Induced fit docking -> Prime MM-GBSA.
3. QM-Polarized Ligand Docking -> Prime MM-GBSA.
1' Which one do you use?
2' What is your normal routine of docking using Schrodinger to final scores?
3' What scoring instead of MM-GBSA do you use either?