For now I consider the best way of docking in Schrodinger Maestro package. I have three types:

1. Grid preparation -> Glide -> Prime MM-GBSA.

2. Induced fit docking -> Prime MM-GBSA.

3. QM-Polarized Ligand Docking -> Prime MM-GBSA.

1' Which one do you use?

2' What is your normal routine of docking using Schrodinger to final scores?

3' What scoring instead of MM-GBSA do you use either?

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