Synthesis: Who knows the method for synthesis of Z-His-Trp-OH?

Who knows the method for synthesis of Z-His-Trp-OH?

05 June 2014 5,929 2 View

How can I identify the structure of Fmoc-Tyr(trt)-OH and remove the Trt group from carboxyl?

I tried to synthesize Fmoc-Tyr(trt)-OH and got a solid that was not dissolved in any solvent, even in a different pH (acid or base). I now doubt that it was Fmoc-Tyr(trt)-OTrt and would like to...

01 February 2014 9,782 5 View

What is the best way to product fmoc-Ser(trt)-OH?

I want to make Fmoc-Ser(trt)-OH, do you know any suitable methods with high yield? I have a problem especially in H-Ser(trt)-OH synthesis, that the alcohol side chain is protected by Trt.

07 August 2013 7,795 5 View

In solid phase synthesis, if I use HOBt in situ, does the excess of HOBt make any problems in coupling step?

In solid phase synthesis, if I use HOBt in situ, does the excess of HOBt make any problems in coupling step?

07 August 2013 7,193 2 View

How should I react rink amide resin?

I am using rink amide to synthesis a peptide with c-terminal as CONHCH2CH3. After cleavage the peptide from resin I will have CONH2. How can I change it to CONHEt with this regards that I have...

07 August 2013 4,425 3 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

flexibility of polymers chain

effect of double bond on the flexibility of polymers

07 April 2021 0 0 View