Synthesis: Who knows the method for synthesis of Z-His-Trp-OH?

More Samira Miss's questions See All

How can I identify the structure of Fmoc-Tyr(trt)-OH and remove the Trt group from carboxyl?

I tried to synthesize Fmoc-Tyr(trt)-OH and got a solid that was not dissolved in any solvent, even in a different pH (acid or base). I now doubt that it was Fmoc-Tyr(trt)-OTrt and would like to...

01 February 2014 9,782 5 View

What is the best way to product fmoc-Ser(trt)-OH?

I want to make Fmoc-Ser(trt)-OH, do you know any suitable methods with high yield? I have a problem especially in H-Ser(trt)-OH synthesis, that the alcohol side chain is protected by Trt.

07 August 2013 7,795 5 View

Rink amide resin?

I am using rink amide to synthesis a peptide with c-terminal as CONHCH2CH3. After cleavage the peptide from resin I will have CONH2. How can I change it to CONHEt with the regards that I have...

07 August 2013 7,379 3 View

In solid phase synthesis, if I use HOBt in situ, does the excess of HOBt make any problems in coupling step?

07 August 2013 7,193 2 View

How should I react rink amide resin?

I am using rink amide to synthesis a peptide with c-terminal as CONHCH2CH3. After cleavage the peptide from resin I will have CONH2. How can I change it to CONHEt with this regards that I have...

07 August 2013 4,425 3 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

fatal error

16 June 2021 0 0 View

flexibility of polymers chain

effect of double bond on the flexibility of polymers

07 April 2021 0 0 View

Formulation of polymer color flakes

I am writing to request some information for making polymer color flakes. I would appreciate the help.

17 March 2021 0 0 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

How Relativistic effects is one reason for lanthanide contraction?

The Lanthanide contraction which is the decrease in ionic radii of the elements in the lanthanide series from atomic number 57, lanthanum, to 71, lutetium, is due to poor shielding of the 4f...

01 March 2021 2,272 4 View