Literatures report that Magnetic Nanoparticles exhibit adverse effect on RBC by hemolysis process [1] , in such case how these particles are used in hyperthermia and other drug delivery applications . Even though the particles are coated with polymeric agent , what will be the fate of these nanoparticles and their effect on RBCs after releasing from polymeric shell. In another view [2,3] these particles were used in clinical trails to identify and treat cancers ; how come this process is possible if it induce hemolysis . Any literature to clarify these aspects ??  

References

[1] http://iopscience.iop.org/article/10.1088/1742-6596/170/1/012019/meta;jsessionid=4919B0226EA721E374CF97A3EE4E795F.c3.iopscience.cld.iop.org

[2]  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134912/

[3] http://www.ncbi.nlm.nih.gov/pubmed/12815134