Rag-2 acts on histones and DNA it seems.

Wouldn't MCs be a more  intersting mediator of PNEI-effects than short-living T/Bcells? MCs have a strong (contradictory, albeit not obligatory) role in Autoimmunity.

kr Gottfried, Berne

Lit:

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/26833222/

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22701454/

http://www.sciencedirect.com/science/article/pii/S0925443911000445