Does anyone have experience with PASS [1] for the use of predicting Bioactivities? I found an old paper [2], but I think it was commercialized and improved over the years. How would you judge the predictions made by the tool? Are they a good indicator? Is there something better out there?
[1] http://www.way2drug.com/passonline/
[2] 10.1093/bioinformatics/16.8.747
Bioactivities prediction also named as target prediction. There are many target prediction (target fishing) tools, such as SWISSTarget(http://www.swisstargetprediction.ch), SEA(https://sea.bkslab.org/).
PASS is good, extensive, software for the purpose. The scores above +8 are worth considering.
Dear Christoph,
First of all, you should know that PASS online is an internationally accredited webserver and considered one of the best and easiest bioinformatic tool to predict the bioactivity of a specific compound.
So, to learn how to use it correctly, i suggest you to carefully read this article (attached).
Best wishes
Thank you all for taking your time to share your experiences and resources!