Please, any lab in Tanzania that is currently doing cytotoxicity tests on cancerous cell lines?

Please, any lab in Tanzania that is currently doing cytotoxicity tests on cancerous cell lines? Kindly let me know Regards

10 November 2018 3,023 0 View

How do I further isolate uncoloured fractions that show peaks on HPLC?

Hello Colleagues, I have several fractions (Hex:EtAc). In one small fraction (about 2mls), I got 6 peaks on HPLC. What do I need to do further or how do I need to separate these compounds,...

09 October 2018 1,547 8 View

How can I prepare a preparative TLC plate (PTLC) using silica gel? or where can I buy already prepared PTLC plates?

Dear Colleagues, Please help. How can I prepare a preparative TLC plate (PTLC) using silica gel? or where can I buy already prepared PTLC plates (Close to Malawi)?

08 September 2018 3,606 3 View

At what point does sequential solvent extraction make more sense? At crude extraction or fractionation?

Dear colleagues, At what point does sequential solvent extraction make more sense? At crude extraction or fractionation stage? One other thought would be to do crude extraction using MeOH and do...

07 August 2018 3,616 4 View

What is the best way of working with extremely busy co-authors in a manuscript?

Dear researchers, Sometimes we have to work with our highly respected co-authors that are extremely too busy to give time to our manuscriots, but for some important reasons, they have to be on the...

05 June 2018 9,949 22 View

What are the most common non-material addiction drugs you know?

What are the most common non-material addiction drugs you know? - Please share if you know any conventional drugs on the market

05 June 2018 2,728 0 View

What is you experience/knowledge about crossing borders with research plant sample extracts?

What is your experience/knowledge about crossing borders with research plant sample extracts? - Any challenges? - Noteworthy details? Please share Thank you and kind regards

05 June 2018 2,226 0 View

Which is better to extract: From fresh or dried plant samples?

which is better to extract from fresh or dried plant samples?

05 June 2018 529 0 View

Is it worthy spending resources on researching orally and intravenously effective drugs from polar compounds?

Dear researchers, I understand that we can get drugs from polar compounds, but these are usually hardly bioavailable. This means the drug has to keep being modified to improve it's bioavailability...

05 June 2018 9,842 6 View

Do you know any medicinal properties of chlorophyll?

Do you know any medicinal properties of chlorophyll? Please share your ideas

05 June 2018 6,720 11 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

Does anyone have any ideas why drug-resistant malaria is increasing in Southeast Asia even when those drugs are no longer used?

When dealing with bacterial toxins, there are three varieties of microbes that develop in your petri dish: toxic, resistant, and susceptible. Initially, there are only toxic and vulnerable...

21 February 2021 6,084 5 View

What is the most prevalent drug related problem in the developed countries?

Detecting the drug related problems is an important step in the pharmaceutical care plan

21 February 2021 5,421 3 View

No title

19 February 2021 8,647 3 View

How to improve dissolution of neosome?

I have made neosome from herbal drug. Neosomes are stable. But I face problems in dissolution. I used minimum ratio of 1:1:0.25 ( Drug:span 60: Cholesterol and GMs. Now how can I active better...

17 February 2021 3,584 1 View

How to determine the drug loading and the drug release capacity of a polymer micelle using UV spectroscopy?

Currently, I am working on PLA-PEG copolymer micelle for the drug delivery system. I have seen several papers where some researcher talks to centrifuge the drug-loaded micelle to separate the...

13 February 2021 5,822 7 View

Should the AUC in a concentration-time graph of a subcutaneous implant be roughly the same for poeple?

I have 2 concentration time curves of a subcut drug implant. the first group has a peak around the 50 day mark where as the second group does not. Both groups received the same implant by the same...

10 February 2021 2,305 3 View

How can I add the metal oxide NP's to the cell lines? I have to make some drug and NP conjuhgates. How much concentration to use? Need some help?

Hi everyone. I am working on metal oxides. I need to make some conjugates of drugs and NP. But I am unsure of what concentrations to make. I have read some articles, but they haven't mentioned...

10 February 2021 3,372 2 View