(*Taking Co-therapy as multiple drugs in single administration)

Key technical advances that have enabled the successful development and commercialization of nano-particulate drug products include advances in biology, materials science and particle engineering, processing, and manufacturing.

Nanoparticle selectivity and efficacy is important in parenteral drug delivery and targeting for cancer and other diseases. Also beside nanoparticle selectivity and efficacy, one important factor is their potential toxicity. Further advances in cell and tissue imaging techniques and other in vitro and in vivo characterization methods of nanomaterials and nanoparticles are necessary to better understand and predict toxicity. Furthermore, development and clinical application of multifunctional nanoparticles which combine disease diagnosis with therapy (nanotheranostics) could prove to be very useful.

Pharmacodynamic and Antiretroviral Activities of Combination Nanoformulated Antiretrovirals in HIV-1–Infected Human Peripheral Blood Lymphocyte–Reconstituted Mice.

Upal Roy et. al.

(Attempts have been made to administer the multiple therapy using Nanoformulation)