Monoavidin/streptavidin for binding large(6-7k bp) biotinylated donor DNA?

18 September 2022 0 7K Report

I found this study, https://www.biorxiv.org/content/10.1101/248179v3.full, and I really want to use the technique, but I'm concerned that monoavidin may have trouble binding a large DNA fragment for knock in. Does anybody have sources or experience with the max size of DNA that can be bound by a monoavidin-biotin link?

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