Mechanism involved in the oxidation of thiazolidine to thiazole by MnO2 ?

More Mohan Tirumalasetty's questions See All

How do regenerate Amberlite XAD 4 resin for further cycles of use for removing 0.5% Sarkosyl from recombinant protein solutions?

I use 0.5% sarkosyl to solubilise recombinant proteins contained in Inclusion bodies of E. coli. sarkosyl very effeciently solubilizes proteins from Inclusion bodies and I am trying to use...

25 July 2024 5,001 2 View

Why do these abnormal charge/discharge curves of coin cell batteries appear?

As shown in the figures, there are several abnormal charge/discharge curves.Each of them may have different problems. I am curious why these situations appeared differently?There are a lot of...

24 July 2024 6,930 1 View

How to troubleshoot the Milliplex Cytokine assay, when I see >OOR/<OOR in my data?

I am conducting cytokine measurements using a multiplex assay. Some of the proteins are yielding results that fall outside the standard curve values, either below (< OOR) or above (> OOR)....

24 June 2024 9,717 0 View

How can formulate Phosphorus 52 and Potassium 34 in liquid ?

formulate Phosphorus 52 and Potassium 34 in liquid

03 June 2024 7,589 2 View

"Range chek error" problem in DSSAT Model?

I was previously using the DSSAT version 4.7 in my PC. Now, I have installed the DSSAT v4.8. Whenever I am trying to simulate the experient is shows "Range chek error". This problem exist even...

13 May 2024 5,894 0 View

I am trying to do X ray peak broadening analysis of nanosheets. How important it is to strip the K-alpha 2 for accurate results?

The stress-strain calculations, energy density GI index calculations are also being done.

02 May 2024 9,963 4 View

How have solitons been interpreted in the protein folding mechanism?

One and two soliton solutions have been obtained while considering the protein folding mechanism of Davydov solitons. What are the dynamics of these soliton solutions that can be obtained in...

25 April 2024 5,241 0 View

Has anyone designed guideRNA for multiple targets using polycistronic-tRNA-gRNA expression system?

I am planning to design guideRNA for multiple targets to express as a polycistronic-tRNA-gRNA expression. I would like to know whether we need to include any linker between the tRNA and guideRNA...

29 March 2024 1,055 0 View

In RG 80 Nobel Prize Winners are listed ,Can we know their area of research and institute of affiliation with country ?

The answer help young researchers get motivated

19 March 2024 3,204 1 View

How to make 10% Boron solution , which content 10% elemental Boron value ?

Procedure for the preparation of 10% Boron liquid.

20 December 2023 9,622 2 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Basis set and input instruction to calculate HOMO and LUMO using Orca for Imidazolium based organic salts?

Hey there, As a synthetic chemist delving into theoretical calculations for my imidazolium-based organic molecules, I would greatly appreciate any guidance on the appropriate input instructions...

09 August 2024 5,444 7 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

Could dyes amplify the spectrum of light to a specific wavelength?

I am interested to know the behavior of dyes toward light. Specifically, Blue dyes re-emit the spectrum, especially from the green zone (known as principal in LED lamps, and blue dyes are known...

05 August 2024 3,290 1 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View

How to improve peaks separation in HPLC?

Hi everyone, I'd like to better separate two close peaks coming from a bioconversion sample, I'm currently using a C18 KromaPhase 4,6mm Ø.I. SCHARLAU, particle size (µm): 10, pore size (Å): 100,...

30 July 2024 435 3 View

What is the best method to detect the chemical composition of pollen ?

I have multiple small samples of grass pollen with anthers. I want to find a method to identify concentrations of proteins, lipids, and other various elements for these samples. any suggestions?

28 July 2024 5,331 1 View

How to separate the stereoisomers compond in reaction mixture?

how to separate the organic reaction stereo isomers compounds are separate from the reaction mixture any simple methods are available

23 July 2024 8,025 4 View

I want to buy Hydrothermal Synthesis Autoclave from any European company. Can anyone suggest any company inside Europe?

Thanks

22 July 2024 1,143 3 View

Hi dear researchers, do you suggest the best and shortest path for chemical synthesis and green synthesis of magnetite(Fe3O4)?

Suggest the best and shortest route for the chemical synthesis and and green synthesis of magnetite(Fe3O4) The chemical synthesis should contain the least dangerous chemicals along with full...

21 July 2024 2,476 2 View

Talaat I. El-Emary

Find in attachment a paper on oxidation of chiral 2-thiazolines using MnO2.

Seth C Rasmussen

This is a basic redox reaction coupled with proton transfer. The thiazolidine is oxidized by the removal of two electrons which is coupled with the loss of two protons for charge neutrality. This oxidation is driven by the fact that the Mn4+ of MnO2 is less favored than the more stable Mn2+, thus Mn takes two electrons (and the two protons) from the thiazolidine to produce thiazole and Mn(OH)2. This is a two electron process and does not really occur stepwise.

The explination provided by Prof. Seth C Rasmussen is very reasonable.