Cecilia,

It has been nearly three decades since I worked in the field. I'm familiar with Wesson's work.

https://www.researchgate.net/profile/Donald_Wesson2/publication/10608525_The_clinical_opiate_withdrawal_scale_COWS/links/571957a408ae30c3f9f2c232/The-clinical-opiate-withdrawal-scale-COWS.pdf

Article The clinical opiate withdrawal scale (COWS)

My entire response did not post.

I found a Cochran review (haven't read it yet) that may contain useful references.

Davoli, M., Amato, L., Clark, N., Farrell, M., Hickman, M., Hill, S., Magrini, N., Poznyak, V., and Schünemann, H. J. (2015), The role of Cochrane reviews in informing international guidelines: a case study of using the Grading of Recommendations, Assessment, Development and Evaluation system to develop World Health Organization guidelines for the psychosocially assisted pharmacological treatment of opioid dependence. Addiction, 110, 891–898. doi: 10.1111/add.12788.

Hope me this is useful.

Regards,

Christopher