Hello!
I have read many 3C papers which have emphasised that the 3C technique can be used to validate long ranging interactions for both cis and trans chromosomal interactions.
However, I have not managed to come across papers (despite my desperate googling) which actually validated trans chromosomal interactions on 3C in humans. I was wondering if anyone could help me with that by recommending me some papers with 3C results on trans chromosomal interaction for on human samples?
I will be very much grateful, thank you!
Pavel Kos
Are you looking specifically for 3c or 3c-based. If 3c-based, then you might want to check these (https://www.nature.com/articles/s41586-020-2744-4 , Article Three-dimensional genome structures of single diploid human cells
) The idea is to use single nucleotide variations (SNV) to distinguish maternal and paternal copies.
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