Why daily dexamethasone given to rats fed high fat/fructose/salt cause very high mortality rate?

rats were given daily dexamethasone in drinking water corresponding to 0.5 mg/kg or 2 mg/kg. These rats are simultaneously fed 25% fat, 3% salt in diet and 10% fructose in drinking water but...

15 February 2021 7,634 2 View

How to access the material properties in COMSOL physics?

Usually, in COMSOL MultiPhysics, there is an option to choose the parameter value from material properties. For example, for choosing Young's modulus value E in the solid mechanics module, one can...

07 January 2021 8,577 8 View

Is it possible to do the optimal sizing in the lab?

Dear Colleagues, recently I'm interested in optimal sizing and techno-economic design integrated into micro-grid using artificial intelligence, and I have many inquiries about it: 1- The...

08 December 2020 7,987 3 View

Quantification of gases with FTIR?

i have quntified the gas sample which contain,H2O, CO2, HF,HCL,CO2,NO2 etc with the help of FTIR Gasmet DX400.. The dilution ratio was 1:10 .Nitrogen was used as a dilution gas. how can I find...

03 November 2020 5,011 2 View

What general setting changed between 4.3b, 5.0 and 5.4 COMSOL MultiPhysics?

I have a model which I ran in three different COMSOL versions and results are different. I haven't changed anything. Does someone has anyidea what global setting changed between the 4.3b, 5.0...

23 September 2020 4,737 4 View

Can we still call nanoparticles (NPs) If they dissolve in water?

I am working on alkali metal NPs and dissolve in water for DLS and zeta. I am a bit confused, when I added in water it instantly dissolves at natural pH. If Nanomaterial dissolves in water, it...

04 September 2020 9,566 6 View

In COMSOL how to save solution of every iterarion?

Is there a way to save solution of each n every iteration taken by the solver in transient study? To be more specific, I am not asking about the time at specified values or time taken by the...

15 August 2020 3,456 2 View

Please suggest a JCR financial mathematics journal names, where to publish an article in a shorter period with very little article processing fee?

It is required to submit an article in good journal

25 May 2020 9,644 7 View

How may the real data be Obtained for verification of Black Scholes equation for two stocks model?

It is required in additional information in the submission of a paper in the journal.

20 May 2020 4,991 1 View

How may we make the regions of the country Mathematically with respect to climatology?

DIfferent Mathematical Techniques are being used for regionalization. For example in different references, the authors regionalize the area across the country under different climates.

10 April 2020 1,829 17 View

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02 March 2021 3,060 3 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Do you need the CMV enhancer before the CMV promotor for a proper function of CMV on the gene that follows?

I'm a student and I have to produce a cell line with a knockin for the NRF2 gene with GFP. I have to put a promotor in front of the GFP because the gene will be too far away from the promotor of...

28 February 2021 7,127 2 View

What could be some reasons why unstimulated monocytes are getting activated?

Im doing PBMC isolation -> CD14+ enrichment using magnetic beads -> stimulation setup. My negative control is just cells in cRPMI but they seem to get activated over and over again.

28 February 2021 7,883 3 View

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28 February 2021 9,936 2 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View

Unknown debris sheets observed in cell culture flasks?

Hi, We culture neural progenitor cells in T175 culture flasks coated with PLO-Laminin. We have successfully grown these cells with our protocol for months. Recently, we observed large sheets...

25 February 2021 3,443 4 View